Harley-Davidson and Indian Motorcycle have long been engaged in a fierce rivalry for dominance in the V-Twin cruiser segment. This competition has pushed both manufacturers to continually evolve and enhance their offerings. For 2025, Harley-Davidson has made a significant leap forward with the release of its most powerful production engine yet—the Milwaukee-Eight 121. This engine not only represents a substantial upgrade in performance but also gives Harley-Davidson a definitive edge in the ongoing power struggle with Indian Motorcycle.
The Milwaukee-Eight 121 V-Twin marks a major milestone for Harley-Davidson. It is the largest production V-Twin ever built by the company, eclipsing the previous generation Milwaukee-Eight 117. With output figures surpassing 120 horsepower and over 130 pound-feet of torque, the 121 delivers a notable improvement in raw performance and capability. This robust power translates to an even more thrilling riding experience, making Harley’s heavyweight cruisers faster and more responsive than ever.
One of the key factors behind the Milwaukee-Eight 121’s improved performance is its enhanced engine displacement. The 121-cubic-inch capacity allows for greater airflow and combustion efficiency, which in turn produces more horsepower and torque. Additionally, the engine features liquid-cooled cylinder heads—an upgrade from the partially liquid-cooled setup found on earlier Milwaukee-Eight engines. This not only improves thermal efficiency but also contributes to better longevity and performance under demanding conditions.
Harley-Davidson has also focused on refining the engine’s overall character. Despite its considerable size and output, the Milwaukee-Eight 121 retains the iconic Harley feel, complete with that signature low-end grunt and a throaty exhaust note. Riders can expect a visceral connection to the machine, one that feels unmistakably like a Harley. The power delivery is smooth and controlled, giving riders confidence whether cruising at low speeds or powering through highway stretches.
Another noteworthy advancement is the integration of updated electronic systems. The Milwaukee-Eight 121 is equipped with advanced ride modes and performance settings that help riders tailor the engine response to their preferences or riding conditions. Combined with improved suspension components and braking systems on the latest models, the 121 contributes to a more modern, refined riding experience without compromising the classic Harley charm.
Beyond performance, the introduction of the Milwaukee-Eight 121 also represents Harley-Davidson’s continued commitment to innovation while staying true to its roots. The engine showcases the company’s engineering prowess and willingness to push the boundaries of traditional cruiser design. At the same time, it preserves the brand’s heritage by maintaining the classic V-Twin layout and unmistakable styling cues.
The debut of the Milwaukee-Eight 121 not only reinforces Harley-Davidson’s standing in the heavyweight cruiser market but also positions it as a leader in the evolving landscape of American motorcycles. It gives Harley a significant advantage over its rival Indian Motorcycle, particularly in the ongoing battle for horsepower and torque supremacy.
Ultimately, the Milwaukee-Eight 121 V-Twin is more than just a big engine—it’s a symbol of Harley-Davidson’s relentless drive to deliver powerful, emotionally engaging motorcycles that appeal to both longtime enthusiasts and a new generation of riders. With this engine at the heart of its newest models, Harley is sending a clear message: the pursuit of V-Twin dominance is far from over, and they intend to lead the way.